Chromosomes of human endometrium.
نویسندگان
چکیده
Evidence is gradually accumulating about acquired somatic chromosome anomalies, particularly those of neoplasms. Unfortunately, control observations are almost entirely lacking. It is generally assumed that all the tissues of the body consist of cells with the normal karyotype as it is seen in cultured lymphocytes or fibroblasts, but this has not yet been shown to be the case. Even bone-marrow, which is rich in dividing cells, has not been the subject of extensive control observations to see how frequently there is a visible departure from the normal karyotype. The present paper is a brief account of the findings in preparations of the chromosomes of human endometrial cells entering mitosis in vivo, where the tissue is histologically normal. Endometrium was chosen as the only accessible normal solid tissue with a sufficiently high mitotic rate.
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عنوان ژورنال:
- Journal of medical genetics
دوره 4 2 شماره
صفحات -
تاریخ انتشار 1967